Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTAFR | P25105 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968454 | 0.91 | ENPP2 (0.39) | ENPP2GRIN1GRIN2BLMNACYP11B1 | |
| SCHEMBL8344845 | 0.91 | PKM (0.41) | ENPP2GRIN1GRIN2BPKMLMNA | |
| SCHEMBL6968344 | 0.90 | ALDH1A1 (0.41) | ENPP2GRIN1GRIN2BLMNATBXAS1 | |
| SCHEMBL6973586 | 0.90 | CYP11B1 (0.41) | ENPP2LMNATBXAS1CYP11B1CYP11B2 | |
| SCHEMBL6970047 | 0.87 | POLB (0.39) | LMNAMAPT | |
| SCHEMBL6975548 | 0.87 | GRIN1 (0.38) | ENPP2GRIN1GRIN2BPTAFRCYP11B2 | |
| SCHEMBL7080841 | 0.86 | GRIN1 (0.36) | ENPP2GRIN1GRIN2BLMNAPTAFR | |
| SCHEMBL7086202 | 0.86 | LMNA (0.41) | ENPP2GRIN1GRIN2BLMNAS1PR3 | |
| SCHEMBL6969811 | 0.85 | GRIN1 (0.37) | ENPP2GRIN1GRIN2BPTAFRCYP11B2 | |
| SCHEMBL6972991 | 0.85 | GRIN1 (0.38) | GRIN1GRIN2BCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |