Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.42 |
| ▸ | RHEB | Q15382 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3865007 | 0.87 | F10 (0.40) | F10PDE10AHDAC6 | |
| SCHEMBL27625018 | 0.82 | F10 (0.41) | F10PDE10AHDAC6 | |
| SCHEMBL27606049 | 0.80 | F10 (0.40) | F10RHEBPDE10AHDAC6 | |
| SCHEMBL3862445 | 0.75 | F10 (0.55) | F10 | |
| SCHEMBL27605913 | 0.73 | CA2 (0.46) | F10 | |
| SCHEMBL8347891 | 0.73 | L3MBTL1 (0.47) | F10 | |
| SCHEMBL1678573 | 0.73 | F10 (0.60) | F10 | |
| SCHEMBL27624772 | 0.73 | F10 (0.41) | F10PDE10AHDAC6 | |
| SCHEMBL8346424 | 0.72 | SIRT2 (0.55) | PDE10A | |
| SCHEMBL3862576 | 0.72 | F10 (0.70) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566789-B2 | Benzimidazole derivatives | MERCK PATENT GMBH (DE) | 2009-07-28 | — | — | US | disclosed |
| US-7566789-B2 | Benzimidazole derivatives | MERCK PATENT GMBH (DE) | 2009-07-28 | — | — | US | disclosed |
| EP-1558247-B1 | BENZIMIDAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2008-02-20 | — | — | EP | disclosed |
| CN-1674893-A | Benzimidazole derivatives | MERCK PATENT GMBH (DE) | 2005-09-28 | — | — | CN | disclosed |
| WO-2004017963-A1 | BENZIMIDAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2004-03-04 | — | — | WO | disclosed |