Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27606049 | 0.89 | F10 (0.40) | F10PDE10AKDM4ENPC1ALDH1A1 | |
| SCHEMBL8348172 | 0.82 | F10 (0.42) | F10PDE10AHDAC6 | |
| SCHEMBL3865007 | 0.80 | F10 (0.40) | F10NPSR1PDE10AKDM4EALDH1A1 | |
| SCHEMBL27605913 | 0.76 | CA2 (0.46) | F10NPSR1L3MBTL1KDM4ENPC1 | |
| SCHEMBL8347891 | 0.76 | L3MBTL1 (0.47) | F10NPSR1L3MBTL1NPC1NFKB1 | |
| SCHEMBL8346424 | 0.75 | SIRT2 (0.55) | NPSR1L3MBTL1PDE10AKDM4ENPC1 | |
| SCHEMBL8346380 | 0.74 | GAA (0.50) | F10NPSR1L3MBTL1PDE10AKDM4E | |
| SCHEMBL27624772 | 0.73 | F10 (0.41) | F10PDE10AKDM4ENPC1ALDH1A1 | |
| SCHEMBL3863014 | 0.73 | CSNK2A2 (0.49) | F10NPSR1PDE10AKDM4ENPC1 | |
| SCHEMBL3861744 | 0.72 | F10 (0.47) | F10KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1674893-A | Benzimidazole derivatives | MERCK PATENT GMBH (DE) | 2005-09-28 | — | — | CN | disclosed |