Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687144 | 0.92 | F10 (0.40) | F10KDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL27605913 | 0.85 | CA2 (0.46) | F10CA2PDGFRBPDGFRAKDM4E | |
| SCHEMBL8346713 | 0.81 | F10 (0.47) | F10PDE3BPDE3ACA2KDM4E | |
| SCHEMBL27606049 | 0.80 | F10 (0.40) | F10KDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL8346380 | 0.79 | GAA (0.50) | F10PDE3BPDE3AKDM4ENPC1 | |
| SCHEMBL3863014 | 0.78 | CSNK2A2 (0.49) | F10KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL27491775 | 0.76 | ALDH1A1 (0.53) | PDE3BPDE3APDGFRBFGFR1PDGFRA | |
| SCHEMBL8346424 | 0.76 | SIRT2 (0.55) | KDM4ENPC1ALDH1A1TP53HPGD | |
| SCHEMBL3861744 | 0.75 | F10 (0.47) | F10KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8347891 | 0.74 | L3MBTL1 (0.47) | F10NPC1NFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1674893-A | Benzimidazole derivatives | MERCK PATENT GMBH (DE) | 2005-09-28 | — | — | CN | disclosed |