Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27624772 | 0.85 | F10 (0.41) | CA2PDGFRBPDGFRANPC1ALDH1A1 | |
| SCHEMBL4687144 | 0.84 | F10 (0.40) | NPC1ALDH1A1GAARAB9AF10 | |
| SCHEMBL8346380 | 0.81 | GAA (0.50) | NPC1ALDH1A1GAARAB9AF10 | |
| SCHEMBL8346713 | 0.79 | F10 (0.47) | CA2ALDH1A1GAAF10KDM4E | |
| SCHEMBL8347891 | 0.77 | L3MBTL1 (0.47) | NPC1RAB9AF10NPSR1L3MBTL1 | |
| SCHEMBL8346424 | 0.76 | SIRT2 (0.55) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL27625018 | 0.76 | F10 (0.41) | NPC1ALDH1A1RAB9AF10KDM4E | |
| SCHEMBL3871590 | 0.74 | F10 (0.38) | NPC1ALDH1A1GAARAB9AF10 | |
| SCHEMBL13759435 | 0.73 | NPSR1 (0.41) | NPC1ALDH1A1RAB9AF10KDM4E | |
| SCHEMBL3863014 | 0.73 | CSNK2A2 (0.49) | NPC1ALDH1A1GAARAB9AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1674893-A | Benzimidazole derivatives | MERCK PATENT GMBH (DE) | 2005-09-28 | — | — | CN | disclosed |