Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PRF1 | P14222 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183029 | 0.75 | ITGB3 (0.41) | AOC3ITGB3ITGAVITGA2BLIPG | |
| SCHEMBL6181740 | 0.69 | MMP14 (0.57) | MMP14 | |
| SCHEMBL6440847 | 0.66 | ADAM17 (0.51) | AOC3ABCB1ABCG2ALDH1A1SMN1; SMN2 | |
| SCHEMBL28608040 | 0.64 | PRMT5 (0.39) | LIPGALDH1A1KDM4EPRF1KMT2A | |
| SCHEMBL13462198 | 0.62 | ADAM17 (0.38) | AOC3ITGB3ITGA2B | |
| SCHEMBL29605363 | 0.62 | ALDH1A1 (0.52) | ABCB1ABCG2ITGB3ITGA2BALDH1A1 | |
| SCHEMBL12878086 | 0.61 | PRMT5 (0.43) | AOC3ITGB3ITGAVITGA2BSMN1; SMN2 | |
| SCHEMBL22207508 | 0.61 | SDCBP (0.37) | ABCB1ABCG2LIPGALDH1A1SMN1; SMN2 | |
| SCHEMBL29209072 | 0.60 | PARP1 (0.39) | AOC3ALDH1A1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL12877713 | 0.60 | ADAM17 (0.44) | ITGB3ITGAVITGA2BSMN1; SMN2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003090751-A1 | PYRIMIDINE-2, 4, 6-TRIONE METALLO-PROTEINASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-11-06 | — | — | WO | disclosed |