Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | CCNC | P24863 | 2/20 | 0.48 |
| ▸ | CDK8 | P49336 | 2/20 | 0.48 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.48 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453190 | 0.90 | CNR1 (0.53) | L3MBTL1LMNACNR1NOS1CCNC | |
| SCHEMBL6950852 | 0.81 | TSHR (0.52) | LMNACNR1ALDH1A1KDM1AMAOA | |
| SCHEMBL7453828 | 0.81 | KCNJ1 (0.60) | L3MBTL1LMNACNR1ALDH1A1MAPT | |
| SCHEMBL11115631 | 0.80 | ALDH1A1 (0.59) | L3MBTL1LMNANOS1ALDH1A1MAPT | |
| SCHEMBL27986680 | 0.79 | GLA (0.47) | L3MBTL1CNR1NOS1ALDH1A1KDM1A | |
| SCHEMBL2154019 | 0.78 | GLA (0.53) | LMNACNR1NOS1ALDH1A1KDM1A | |
| SCHEMBL19442424 | 0.78 | TAAR1 (0.56) | LMNACNR1NOS1ALDH1A1MAPT | |
| SCHEMBL8768922 | 0.78 | CXCR2 (0.50) | L3MBTL1LMNACCNCCDK8CDKN1A | |
| SCHEMBL6962952 | 0.78 | DRD2 (0.49) | LMNAALDH1A1FAAHKDM1AMAOA | |
| SCHEMBL7462625 | 0.77 | NOS1 (0.45) | L3MBTL1LMNACNR1NOS1CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942544-A | α-branched anilines, toluenes, and analogs thereof as factor Xa inhibitors | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-24 | — | — | US | disclosed |