Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 5/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552392 | 0.90 | ADAMTS5 (0.35) | ADAMTS5ITGB3ITGA2BMAPTADAMTS4 | |
| SCHEMBL8352452 | 0.77 | ITGB3 (0.39) | ITGB3ITGA2BL3MBTL1AKR1C3F10 | |
| SCHEMBL8356608 | 0.74 | AKR1C3 (0.38) | ITGB3ITGA2BMAPTKDM4EAKR1C3 | |
| SCHEMBL8356623 | 0.70 | ITGB3 (0.38) | ITGB3ITGA2BL3MBTL1F10 | |
| SCHEMBL8776264 | 0.70 | ALDH1A1 (0.46) | POLBADAMTS5MAPTADAMTS4KDM4E | |
| SCHEMBL8355533 | 0.70 | ITGB3 (0.36) | ITGB3ITGA2BF10 | |
| SCHEMBL8351077 | 0.69 | F10 (0.37) | ITGB3ITGA2BF10 | |
| SCHEMBL7790314 | 0.69 | ALDH1A1 (0.47) | POLBADAMTS5ITGB3ITGA2BMAPT | |
| SCHEMBL7790836 | 0.68 | ITGB3 (0.46) | ITGB3ITGA2BMAPTKDM4EALDH1A1 | |
| SCHEMBL8356522 | 0.68 | NOTUM (0.38) | ITGB3ITGA2BKDM4EAKR1C3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972947-A | ANTICOAGULANT, CARDIOVASCULAR DISORDERS, ANTIINFLAMMATORY AGENTS, OSTEOPOROSIS, ANTITUMOR AGENT | ROCHE DIAGNOSTICS GMBH (DE) | 1999-10-26 | — | — | US | disclosed |
| EP-0839147-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003072-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-30 | — | — | WO | disclosed |