Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 7/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8355447 | 0.90 | POLB (0.38) | ADAMTS5ADAMTS4KDM4EALDH1A1MAPT | |
| SCHEMBL8554007 | 0.77 | HRH3 (0.42) | HRH3ITGB3ITGA2B | |
| SCHEMBL8552905 | 0.71 | SIGMAR1 (0.33) | — | |
| SCHEMBL8595580 | 0.71 | HTR7 (0.34) | HRH3 | |
| SCHEMBL8551745 | 0.69 | HRH3 (0.36) | HRH3ITGB3ITGA2B | |
| SCHEMBL8776264 | 0.68 | ALDH1A1 (0.46) | ADAMTS5ADAMTS4KDM4EALDH1A1MAPT | |
| SCHEMBL8352452 | 0.67 | ITGB3 (0.39) | HRH3ITGB3ITGA2B | |
| SCHEMBL7790314 | 0.66 | ALDH1A1 (0.47) | ADAMTS5ADAMTS4KDM4EALDH1A1MAPT | |
| SCHEMBL8550693 | 0.66 | HTR2B (0.43) | HRH3ITGB3ITGA2B | |
| SCHEMBL7790836 | 0.66 | ITGB3 (0.46) | KDM4EALDH1A1MAPTHIF1AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839147-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003072-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-30 | — | — | WO | disclosed |