Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665342 | 0.78 | — | — | |
| SCHEMBL8488364 | 0.78 | HPGD (0.46) | MTNR1ANPC1RAB9AALDH1A1F2 | |
| SCHEMBL10425014 | 0.78 | PNMT (0.39) | MTNR1ANPC1RAB9AHTTKMT2A | |
| SCHEMBL9618306 | 0.78 | TSHR (0.57) | HTTKMT2AALDH1A1IDO1TAAR1 | |
| SCHEMBL10425013 | 0.78 | MTNR1A (0.38) | MTNR1ANPC1RAB9AHTTKMT2A | |
| SCHEMBL7662207 | 0.78 | — | — | |
| SCHEMBL5185932 | 0.78 | GABRA1 (0.42) | KMT2AALDH1A1LMNAMEN1CYP2D6 | |
| SCHEMBL4014038 | 0.77 | ALDH1A1 (0.54) | NPC1RAB9AHTTKMT2AALDH1A1 | |
| SCHEMBL4023664 | 0.77 | NPC1 (0.61) | NPC1RAB9AHTTKMT2AALDH1A1 | |
| SCHEMBL10310299 | 0.77 | RIPK1 (0.49) | KMT2AALDH1A1LMNASMN1; SMN2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040882-A2 | STEREOSELECTIVE Tc-99m LIGANDS | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1999-08-19 | — | — | WO | disclosed |