Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 4/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.49 |
| ▸ | CCKBR | P32239 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11016370 | 0.87 | GABRA1 (0.46) | GABRA5GABRA2GABRB2GABRA1GABRG2 | |
| SCHEMBL7310152 | 0.87 | OPRK1 (0.60) | GABRA5GABRA2GABRB2GABRA1GABRG2 | |
| SCHEMBL7721824 | 0.84 | GABRA1 (0.62) | GABRA5GABRA2GABRB2GABRA1GABRG2 | |
| SCHEMBL7308087 | 0.83 | LMNA (0.58) | GABRA5GABRA2GABRB2GABRA1GABRG2 | |
| SCHEMBL1313752 | 0.78 | GABRA1 (0.60) | GABRA5GABRA2GABRB2GABRA1GABRG2 | |
| SCHEMBL7307080 | 0.78 | OPRK1 (0.58) | GABRA5GABRA2GABRB2GABRA1GABRG2 | |
| SCHEMBL7316446 | 0.77 | OPRK1 (0.57) | GABRA5GABRA2GABRB2GABRA1GABRG2 | |
| SCHEMBL9565440 | 0.77 | GABRA5 (0.45) | GABRA5GABRA2GABRB2GABRA1GABRG2 | |
| SCHEMBL11016146 | 0.77 | GABRA1 (0.45) | GABRA5GABRA2GABRB2GABRA1GABRG2 | |
| SCHEMBL1311112 | 0.77 | OPRK1 (0.63) | GABRA5GABRA2GABRB2GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100261711-A1 | SELECTIVE ANTICONVULSANT AGENTS AND THEIR USES | WISYS TECHNOLOGY FOUNDATION (US) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261711-A1 | SELECTIVE ANTICONVULSANT AGENTS AND THEIR USES | GABRA5, GABRA6, GABRA2 | GABRA5 1/4885GABRA2 3/4885GABRB2 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.