Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8365008 | 0.79 | SMN1; SMN2 (0.39) | P2RX7SMN1; SMN2MAPTALDH1A1MAOB | |
| SCHEMBL8366392 | 0.77 | KDM4E (0.43) | NOTUMSMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL6956182 | 0.73 | BCHE (0.36) | SMN1; SMN2MAPTALDH1A1PRKDC | |
| SCHEMBL8366389 | 0.65 | CTSD (0.45) | NOTUMMAPTALDH1A1POLBROCK2 | |
| SCHEMBL5068884 | 0.64 | NPC1 (0.55) | P2RX7SMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL11548757 | 0.64 | BACE1 (0.56) | P2RX7SMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL6931240 | 0.63 | P2RX7 (0.54) | P2RX7SMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL6748172 | 0.63 | BRD4 (0.56) | NOTUMALDH1A1MAOB | |
| SCHEMBL11545241 | 0.63 | SMN1; SMN2 (0.53) | P2RX7SMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL12528063 | 0.62 | ALDH1A1 (0.57) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929089-A | ANTISEROTONINE AGENT | SYNTHELABO (FR) | 1999-07-27 | — | — | US | disclosed |