Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846694 | 0.86 | L3MBTL1 (0.56) | L3MBTL1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL22723991 | 0.84 | L3MBTL1 (0.55) | L3MBTL1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL27361867 | 0.76 | RAB9A (0.49) | L3MBTL1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL13479963 | 0.75 | — | — | |
| SCHEMBL6971473 | 0.73 | — | — | |
| SCHEMBL875579 | 0.72 | TMPRSS15 (0.49) | L3MBTL1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL22961451 | 0.72 | CHRM2 (0.49) | L3MBTL1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL19520914 | 0.71 | TMPRSS15 (0.49) | L3MBTL1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL15871987 | 0.70 | SMPD1 (0.48) | L3MBTL1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL285859 | 0.70 | CHRM2 (0.47) | L3MBTL1CHRM2CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143421-B2 | Broadspectrum substituted benzimidazole sulfonamide HIV protease inhibitors | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2012-03-27 | — | — | US | disclosed |
| US-20090203743-A1 | SMALL MOLECULE ENTRY INHIBITORS | SURLERAUX DOMINIQUE LOUIS | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203743-A1 | SMALL MOLECULE ENTRY INHIBITORS | NR0B1, LTC4S, LTB4R | L3MBTL1 2244/4885CHRM2 452/4885CHRM4 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.