Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | VDR | P11473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | XBP1 | P17861 | 2/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368446 | 0.80 | VDR (0.58) | KMT2AVDRKDM4EMAPTALDH1A1 | |
| SCHEMBL10787195 | 0.77 | KMT2A (0.67) | KMT2AVDRKDM4EMAPTALDH1A1 | |
| SCHEMBL8778040 | 0.76 | PARL (0.53) | KMT2AVDRKDM4EMAPTALDH1A1 | |
| SCHEMBL12051386 | 0.73 | PARL (0.37) | KMT2AVDRKDM4EMAPTALDH1A1 | |
| SCHEMBL9986033 | 0.73 | KMT2A (0.43) | KMT2AKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL27627188 | 0.71 | ALDH1A1 (0.42) | KMT2AMAPTALDH1A1HTTMEN1 | |
| SCHEMBL9986290 | 0.70 | MMP2 (0.42) | KMT2AMAPTALDH1A1HTTMEN1 | |
| SCHEMBL8370936 | 0.69 | POLB (0.33) | KMT2AVDRKDM4EMAPTALDH1A1 | |
| SCHEMBL8837665 | 0.69 | MEN1 (0.53) | KMT2AHTTHSD17B2MEN1HSD11B1 | |
| SCHEMBL12032450 | 0.67 | MCOLN3 (0.46) | KMT2AKDM4EMAPTALDH1A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510440-B1 | Positive-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | CLARIANT GMBH (DE) | 1999-01-13 | — | — | EP | disclosed |
| EP-0510443-B1 | Negative-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | HOECHST AG (DE) | 1995-03-22 | — | — | EP | disclosed |
| EP-0510442-A1 | Substituted 1-sulfonyloxy-2-pyridones, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-28 | — | — | EP | disclosed |
| EP-0510443-A1 | Negative-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-28 | — | — | EP | disclosed |
| EP-0510440-A1 | Positive-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-28 | — | — | EP | disclosed |