Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | PARL | Q9H300 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778040 | 0.82 | PARL (0.53) | MMP2HTTPARLALDH1A1MEN1 | |
| SCHEMBL9986376 | 0.81 | ALDH1A1 (0.48) | HTTCA2CA9CA1CA12 | |
| SCHEMBL8368446 | 0.80 | VDR (0.58) | MMP2HTTCA2CA1PARL | |
| SCHEMBL12051386 | 0.77 | PARL (0.37) | HTTPARLALDH1A1LMNAMEN1 | |
| SCHEMBL9986033 | 0.77 | KMT2A (0.43) | CA2CA9CA1CA12CA14 | |
| SCHEMBL11022400 | 0.75 | KDM4E (0.69) | HTTPARLALDH1A1LMNAMEN1 | |
| SCHEMBL12032450 | 0.72 | MCOLN3 (0.46) | HTTALDH1A1LMNAMEN1MAPT | |
| SCHEMBL2957966 | 0.72 | PARL (0.62) | MMP2CA2CA9CA1CA12 | |
| SCHEMBL11041999 | 0.71 | HTT (0.59) | HTTCA2CA9CA1CA12 | |
| SCHEMBL6650340 | 0.71 | CA1 (0.44) | MMP2HTTCA2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889638-B2 | Stimulus-triggered prodrugs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-18 | — | — | US | disclosed |
| US-8889638-B2 | Stimulus-triggered prodrugs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-18 | — | — | US | disclosed |
| US-20110312905-A1 | STIMULUS-TRIGGERED PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312905-A1 | STIMULUS-TRIGGERED PRODRUGS | PREP, ADAM10, DNPEP | MMP2 137/4885HTT 3890/4885CA2 749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.