Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PARL | Q9H300 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778040 | 0.86 | PARL (0.53) | VDRALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL12051386 | 0.80 | PARL (0.37) | VDRALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL9986290 | 0.80 | MMP2 (0.42) | ALDH1A1CA1CA2KMT2AMEN1 | |
| SCHEMBL8368449 | 0.80 | KMT2A (0.40) | VDRALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL10395507 | 0.78 | VDR (0.57) | VDRALDH1A1KDM4EHPGDCA1 | |
| SCHEMBL12032450 | 0.76 | MCOLN3 (0.46) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL8370936 | 0.75 | POLB (0.33) | VDRALDH1A1KDM4EHPGDCA1 | |
| SCHEMBL9044989 | 0.75 | VDR (0.51) | VDRALDH1A1KDM4EHPGDCA1 | |
| SCHEMBL29370293 | 0.73 | VDR (1.00) | VDRALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL64277 | 0.73 | VDR (1.00) | VDRALDH1A1KDM4EHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889638-B2 | Stimulus-triggered prodrugs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-18 | — | — | US | disclosed |
| US-8889638-B2 | Stimulus-triggered prodrugs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-18 | — | — | US | disclosed |
| US-8889638-B2 | Stimulus-triggered prodrugs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-18 | — | — | US | disclosed |
| US-20110312905-A1 | STIMULUS-TRIGGERED PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-22 | — | — | US | disclosed |
| US-20110312905-A1 | STIMULUS-TRIGGERED PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-22 | — | — | US | disclosed |
| US-20110312905-A1 | STIMULUS-TRIGGERED PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-22 | — | — | US | disclosed |
| US-20100093883-A1 | Hydroxamic Esters as Photoinitiators | LAMBERTI SPA (IT) | 2010-04-15 | — | — | US | disclosed |
| US-20100093883-A1 | Hydroxamic Esters as Photoinitiators | LAMBERTI SPA (IT) | 2010-04-15 | — | — | US | disclosed |
| CN-101472929-A | Process for producing high-purity prasugrel and acid addition salt thereof | DAIICHI SANKYO CO LTD (JP) | 2009-07-01 | — | — | CN | disclosed |
| WO-2008104436-A1 | HYDROXAMIC ESTERS AS PHOTOINITIATORS | LAMBERTI SPA (IT) | 2008-09-04 | — | — | WO | disclosed |
| EP-0510440-B1 | Positive-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | CLARIANT GMBH (DE) | 1999-01-13 | — | — | EP | disclosed |
| EP-0510443-B1 | Negative-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | HOECHST AG (DE) | 1995-03-22 | — | — | EP | disclosed |
| US-5286867-A | Substituted 1-sulfonyloxy-2-pyridones and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-15 | — | — | US | disclosed |
| US-5230985-A | NEGATIVE-WORKING RADIATION-SENSITIVE MIXTURES, AND RADIATION-SENSITIVE RECORDING MATERIAL PRODUCED WITH THESE MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-27 | — | — | US | disclosed |
| US-5229254-A | Photoresists, printing plates, sulfonic acid generators | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-20 | — | — | US | disclosed |
| EP-0510442-A1 | Substituted 1-sulfonyloxy-2-pyridones, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-28 | — | — | EP | disclosed |
| EP-0510443-A1 | Negative-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-28 | — | — | EP | disclosed |
| EP-0510440-A1 | Positive-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312905-A1 | STIMULUS-TRIGGERED PRODRUGS | PREP, ADAM10, DNPEP | VDR 1215/4885ALDH1A1 1555/4885KDM4E 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.