Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 11/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008337 | 0.87 | CA1 (0.59) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL3803914 | 0.87 | CA1 (0.59) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL27744228 | 0.83 | ADRA2A (0.50) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL6558753 | 0.83 | CA12 (0.61) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL3441770 | 0.83 | PNMT (0.50) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL6202191 | 0.81 | DRD2 (0.58) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL2076586 | 0.80 | WDR5 (0.51) | — | |
| SCHEMBL2241528 | 0.80 | TDP1 (0.52) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL9716393 | 0.80 | PNMT (0.55) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL29370265 | 0.79 | PNMT (0.57) | PNMTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052857-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1999-10-21 | — | — | WO | disclosed |