Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30360391 | 0.72 | TYR (0.44) | ALDH1A1GAAALOX12HTTHIF1A | |
| SCHEMBL1760433 | 0.72 | TYR (0.44) | ALDH1A1GAAALOX12HTTHIF1A | |
| SCHEMBL7519203 | 0.69 | LMNA (0.37) | — | |
| SCHEMBL27565810 | 0.68 | HSP90AA1 (0.39) | ALDH1A1GAAALOX12HTTHIF1A | |
| SCHEMBL27959750 | 0.65 | CA3 (0.36) | ALDH1A1GAAALOX12HTTHIF1A | |
| SCHEMBL27959754 | 0.63 | CA3 (0.34) | ALDH1A1GAAALOX12HTTHIF1A | |
| SCHEMBL25229039 | 0.62 | TRPA1 (0.46) | ALDH1A1GAAALOX12HTTHIF1A | |
| SCHEMBL478565 | 0.62 | LMNA (0.46) | ALDH1A1GAAALOX12HTTHIF1A | |
| SCHEMBL27407567 | 0.62 | ALOX12 (0.41) | ALDH1A1GAAALOX12HTTHIF1A | |
| SCHEMBL7522318 | 0.62 | ALDH1A1 (0.40) | ALDH1A1ALOX12HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900225-A1 | ALKYL-4-SILYL-PHENOLS AND ESTERS THEREOF AS ANTIATHEROSCLEROTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997041129-A1 | ALKYL-4-SILYL-PHENOLS AND ESTERS THEREOF AS ANTIATHEROSCLEROTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-06 | — | — | WO | disclosed |