Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA1 | Q09470 | 5/20 | 0.52 |
| ▸ | KCNAB1 | Q14722 | 5/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulofenur SCHEMBL29359159 | 0.87 | KCNA1 (0.65) | KCNA1KCNAB1CA12CA1CA2 | |
| Sulofenur SCHEMBL4174 | 0.87 | KCNA1 (0.65) | KCNA1KCNAB1CA12CA1CA2 | |
| SCHEMBL8878995 | 0.84 | KCNA1 (0.65) | KCNA1KCNAB1CA12CA1CA2 | |
| SCHEMBL8879166 | 0.76 | KCNA1 (0.56) | KCNA1KCNAB1CA12CA1CA2 | |
| SCHEMBL8794803 | 0.76 | CA12 (0.55) | KCNA1KCNAB1CA12CA1CA2 | |
| SCHEMBL15865553 | 0.76 | RAB9A (0.67) | KCNA1KCNAB1CA12CA1CA2 | |
| SCHEMBL28766991 | 0.76 | NPC1 (0.67) | KCNA1KCNAB1CA12CA1CA2 | |
| SCHEMBL8793567 | 0.73 | CA12 (0.52) | KCNA1KCNAB1CA12CA1CA2 | |
| SCHEMBL10698263 | 0.72 | KCNA1 (0.55) | KCNA1KCNAB1CA12CA1CA2 | |
| SCHEMBL8877626 | 0.72 | PKM (0.70) | KCNA1KCNAB1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932742-A | CHEMICAL INTERMEDIATE TO ACTIVE ANTITUMOR AGENT | DONG WHA PHARM. IND. CO., LTD. (KR) | 1999-08-03 | — | — | US | disclosed |
| US-5929103-A | ANTICARCINOGENIC AGENTS | DONG WHA PHARM. IND. CO., LTD. (KR) | 1999-07-27 | — | — | US | disclosed |