Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441858 | 0.95 | CYP2D6 (0.44) | POLBMAPTCYP2D6CYP2C19DRD2 | |
| SCHEMBL8439867 | 0.90 | LMNA (0.44) | POLBPDE2ASMN1; SMN2 | |
| SCHEMBL8522389 | 0.86 | POLB (0.44) | TDP1POLBMAPTCYP1A2CYP2D6 | |
| SCHEMBL8441415 | 0.86 | LMNA (0.43) | TSHRCYP1A2CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL8442148 | 0.84 | KMT2A (0.44) | POLBMAPTTSHR | |
| SCHEMBL8672721 | 0.83 | PTGS2 (0.40) | POLBMAPTTSHRSMN1; SMN2 | |
| SCHEMBL8551375 | 0.82 | KDM4E (0.39) | POLBMAPTTSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL8438242 | 0.81 | CHRNB4 (0.44) | — | |
| SCHEMBL8668966 | 0.79 | SMN1; SMN2 (0.38) | MAPTSMN1; SMN2HTR1ADRD3 | |
| SCHEMBL8552372 | 0.78 | PTGS2 (0.36) | POLBMAPTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916904-A | ANTIULCER | EISAI CO., LTD. (JP) | 1999-06-29 | — | — | US | disclosed |