Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7909434 | 0.92 | SMN1; SMN2 (0.50) | PKMGLASMN1; SMN2GAATSHR | |
| SCHEMBL8382459 | 0.86 | PKM (0.51) | PKMGLASMN1; SMN2GAATSHR | |
| SCHEMBL8384378 | 0.83 | MAPK1 (0.47) | PKMSMN1; SMN2GAATSHRALOX15 | |
| SCHEMBL19146051 | 0.80 | PKM (0.42) | PKMSMN1; SMN2TSHRKDM1ATPSAB1 | |
| SCHEMBL5856719 | 0.79 | SIGMAR1 (0.55) | GLASMN1; SMN2TSHRSIGMAR1KDM1A | |
| SCHEMBL11570934 | 0.78 | TSHR (0.58) | GLASMN1; SMN2TSHRSIGMAR1LMNA | |
| SCHEMBL8384455 | 0.77 | PKM (0.45) | PKMGLAGAATSHRALOX15 | |
| SCHEMBL7909740 | 0.77 | SMN1; SMN2 (0.46) | PKMGLASMN1; SMN2SIGMAR1KDM1A | |
| SCHEMBL21068880 | 0.75 | TSHR (0.47) | GLASMN1; SMN2TSHRSIGMAR1HRH2 | |
| SCHEMBL9462329 | 0.75 | SIGMAR1 (0.48) | GLASMN1; SMN2TSHRSIGMAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908843-A | Piperazine compounds as fibrinogen inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-06-01 | — | — | US | disclosed |