Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8384455 | 0.91 | PKM (0.45) | MAPK1PKMGAASIGMAR1ALDH1A1 | |
| SCHEMBL7913433 | 0.84 | GAA (0.50) | MAPK1PKMGAAALDH1A1MAPT | |
| SCHEMBL8380855 | 0.83 | PKM (0.45) | SMN1; SMN2PKMGAASIGMAR1ALDH1A1 | |
| SCHEMBL7909434 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMGAAALDH1A1MAPT | |
| SCHEMBL7900115 | 0.77 | MAPK1 (0.46) | MAPK1PKMGAAALDH1A1MAPT | |
| SCHEMBL23854090 | 0.75 | CYP1A2 (0.67) | MAPK1CYP1A2SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL8512409 | 0.75 | CYP1A2 (0.67) | MAPK1CYP1A2SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL8947664 | 0.75 | — | — | |
| SCHEMBL8377176 | 0.75 | CYP1A2 (0.78) | MAPK1CYP1A2SMN1; SMN2TSHR | |
| SCHEMBL7913360 | 0.73 | TPSAB1 (0.37) | MAPK1SMN1; SMN2SIGMAR1TSHRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908843-A | Piperazine compounds as fibrinogen inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-06-01 | — | — | US | disclosed |