Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8384378 | 0.91 | MAPK1 (0.47) | PKMGAAALOX15TSHRHSD17B10 | |
| SCHEMBL7913433 | 0.87 | GAA (0.50) | PKMGAAALOX15TSHRHSD17B10 | |
| SCHEMBL7909434 | 0.82 | SMN1; SMN2 (0.50) | PKMGAAALOX15TSHRHSD17B10 | |
| SCHEMBL7913360 | 0.81 | TPSAB1 (0.37) | TSHRGLAHTR7HTR1AITGB3 | |
| SCHEMBL7900115 | 0.79 | MAPK1 (0.46) | PKMGAAALOX15TSHRHSD17B10 | |
| SCHEMBL8380855 | 0.77 | PKM (0.45) | PKMGAAALOX15TSHRHSD17B10 | |
| SCHEMBL8382459 | 0.75 | PKM (0.51) | PKMGAAALOX15TSHRHSD17B10 | |
| SCHEMBL19146559 | 0.74 | KDM4E (0.52) | PKMGAAALOX15TSHRHSD17B10 | |
| SCHEMBL9621522 | 0.73 | GLA (0.57) | HSD17B10ALDH1A1MAPTGLAHTR7 | |
| SCHEMBL8685695 | 0.73 | GLA (0.57) | HSD17B10ALDH1A1MAPTGLAHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908843-A | Piperazine compounds as fibrinogen inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-06-01 | — | — | US | disclosed |