SCHEMBL838141

SCHEMBL838141

O=S(=O)(O)c1ccc2ccc(SOOO)cc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
HSD17B10 Q99714 4/20 0.41
CASP6 P55212 4/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 1/20 0.41
PTPN11 Q06124 3/20 0.40
SNCA P37840 2/20 0.40
NT5E P21589 4/20 0.36
NSD2 O96028 3/20 0.34
LMNA P02545 2/20 0.33
DUSP3 P51452 2/20 0.33
PTPN5 P54829 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP1A2 P05177 1/20 0.32
CASP7 P55210 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL838048 0.95 SNCA (0.44) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL14496682 0.88 ALDH1A1 (0.43) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL13538730 0.83 LMNA (0.45) ALDH1A1HSD17B10PTPN11NT5ELMNA
SCHEMBL13397782 0.82 CASP6 (0.56) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL13347005 0.80 BCL2 (0.37) ALDH1A1HSD17B10PTPN11TDP1
SCHEMBL2736406 0.80 ALDH1A1 (0.46) ALDH1A1HSD17B10CASP6PTPN11SNCA
SCHEMBL860127 0.79 PTPN11 (0.44) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL13742960 0.79 CASP6 (0.52) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL29381755 0.78 ALDH1A1 (0.59) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL29574227 0.78 ALDH1A1 (0.59) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426102-B2 Lithographic printing plate precursor and plate making method FUJIFILM CORPORATION (JP) 2013-04-23 US disclosed
US-8399172-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2013-03-19 US disclosed
US-8309294-B2 2012-11-13 US disclosed
US-8304171-B2 Plate making method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-8221957-B2 Planographic printing plate precursor and printing method using the same FUJIFILM CORPORATION (JP) 2012-07-17 US disclosed
US-8211678-B2 Ethanol preparation method HONDA MOTOR CO., LTD. (JP) 2012-07-03 US disclosed
US-8187791-B2 Lithographic printing plate precursor and plate making method thereof FUJIFILM CORPORATION (JP) 2012-05-29 US disclosed
US-8167144-B2 Water separation membrane HONDA MOTOR CO., LTD. (JP) 2012-05-01 US disclosed
US-8142982-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-8142983-B2 Lithographic printing plate precursor and method of lithographic printing FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-20090111049-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-04-30 US disclosed
US-20090047601-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-02-19 US disclosed
US-20080318155-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD FUJIFILM CORPORATION (JP) 2008-12-25 US disclosed
US-20080254384-A1 Cyanine dye containing methine chain and onium salt structure FUJIFILM CORPORATION (JP) 2008-10-16 US disclosed
US-20080233516-A1 NEGATIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed
US-20080096132-A1 mixing a polymerizable monomer in which acrylonitrile accounts for 70% by weight or more of a total of the polymerizable monomer, water and an alkali metal persulfate polymerization initiator to conduct emulsion polymerization; distilling off unpolymerized monomers; chemical resistance film, gas barrier FUJIFILM CORPORATION 2008-04-24 US disclosed
US-20080087183-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2008-04-17 US disclosed
US-20070215300-A1 Solvents For Use In The Treatment Of Lignin-Containing Materials VIRIDIAN CHEMICAL PTY LTD (AU) 2007-09-20 US disclosed
US-20070214987-A1 Lithographic printing plate precursor FUJIFILM CORPORATION 2007-09-20 US disclosed
US-20070042293-A1 Including an aromatic diphosphonium compound along with an addition polymerization promoter, unsaturated compound, protective layeron an sluminium support; laser recording having excellent ink receptibility during printing and printing durability; strength; on-press development; image strength FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080254384-A1 Cyanine dye containing methine chain and onium salt structure INMT, MGMT, IK ALDH1A1 2220/4885HSD17B10 2992/4885CASP6 2237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.