SCHEMBL838048

SCHEMBL838048

O=S(=O)(O)c1ccc2cc(SOOO)ccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.44
PTPN11 Q06124 3/20 0.43
ALDH1A1 P00352 5/20 0.42
HSD17B10 Q99714 4/20 0.42
CASP6 P55212 4/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 1/20 0.42
NT5E P21589 4/20 0.37
NSD2 O96028 3/20 0.35
LMNA P02545 2/20 0.34
DUSP3 P51452 2/20 0.34
PTPN5 P54829 2/20 0.34
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
CYP1A2 P05177 1/20 0.33
CASP7 P55210 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL838141 0.95 ALDH1A1 (0.41) SNCAPTPN11ALDH1A1HSD17B10CASP6
SCHEMBL14496682 0.89 ALDH1A1 (0.43) SNCAPTPN11ALDH1A1HSD17B10CASP6
SCHEMBL13538730 0.84 LMNA (0.45) PTPN11ALDH1A1HSD17B10NT5ELMNA
SCHEMBL13397782 0.83 CASP6 (0.56) PTPN11ALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL13347005 0.81 BCL2 (0.37) PTPN11ALDH1A1HSD17B10TDP1
SCHEMBL2736406 0.81 ALDH1A1 (0.46) SNCAPTPN11ALDH1A1HSD17B10CASP6
SCHEMBL860127 0.80 PTPN11 (0.44) PTPN11ALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL13742960 0.80 CASP6 (0.52) PTPN11ALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL13428187 0.79 LMNA (0.41) PTPN11ALDH1A1HSD17B10NT5ELMNA
SCHEMBL13310832 0.79 LMNA (0.41) PTPN11ALDH1A1HSD17B10NT5ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8399172-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2013-03-19 US disclosed
US-8221957-B2 Planographic printing plate precursor and printing method using the same FUJIFILM CORPORATION (JP) 2012-07-17 US disclosed
US-8211678-B2 Ethanol preparation method HONDA MOTOR CO., LTD. (JP) 2012-07-03 US disclosed
US-8167144-B2 Water separation membrane HONDA MOTOR CO., LTD. (JP) 2012-05-01 US disclosed
US-8142982-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-8142978-B2 Planographic printing plate precursor and printing method using the same FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-8113116-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-02-14 US disclosed
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-7935473-B2 Photosensitive composition, lithographic printing plate precursor, lithographic printing method, and novel cyanine dyes FUJIFILM CORPORATION (JP) 2011-05-03 US disclosed
US-20100071574-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
US-20090114108-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-05-07 US disclosed
US-20090111049-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-04-30 US disclosed
US-20090098410-A1 Trimethine Dimer Compound and Optical Recording Medium Using the Same MITSUI CHEMICALS, INC. (JP) 2009-04-16 US disclosed
US-20090047601-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-02-19 US disclosed
US-20080286685-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080254384-A1 Cyanine dye containing methine chain and onium salt structure FUJIFILM CORPORATION (JP) 2008-10-16 US disclosed
US-20080233516-A1 NEGATIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed
US-20080096132-A1 mixing a polymerizable monomer in which acrylonitrile accounts for 70% by weight or more of a total of the polymerizable monomer, water and an alkali metal persulfate polymerization initiator to conduct emulsion polymerization; distilling off unpolymerized monomers; chemical resistance film, gas barrier FUJIFILM CORPORATION 2008-04-24 US disclosed
US-20080087183-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2008-04-17 US disclosed
US-20070214987-A1 Lithographic printing plate precursor FUJIFILM CORPORATION 2007-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098410-A1 Trimethine Dimer Compound and Optical Recording Medium Using the Same TXNL1, TMCO1, TFPI2 SNCA 2738/4885PTPN11 2830/4885ALDH1A1 3651/4885
US-20080254384-A1 Cyanine dye containing methine chain and onium salt structure INMT, MGMT, IK SNCA 2600/4885PTPN11 2145/4885ALDH1A1 2220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.