Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.36 |
| ▸ | S100A10 | P60903 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 2/20 | 0.33 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.32 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.32 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.32 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.32 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12047410 | 0.87 | TSHR (0.38) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL13029820 | 0.83 | HTR6 (0.45) | ALDH1A1TSHRSMN1; SMN2ANXA2S100A10 | |
| SCHEMBL13059484 | 0.83 | TSHR (0.36) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL13520405 | 0.83 | GAA (0.39) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL13520390 | 0.82 | MAPK1 (0.36) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL2736407 | 0.82 | LCK (0.36) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL838048 | 0.81 | SNCA (0.44) | ALDH1A1HSD17B10TSHRTDP1PTPN11 | |
| SCHEMBL13039674 | 0.81 | HDAC1 (0.36) | ALDH1A1HSD17B10TSHRTDP1PTPN11 | |
| SCHEMBL10330721 | 0.80 | ANXA2 (0.37) | ALDH1A1TSHRSMN1; SMN2PTPN11ANXA2 | |
| SCHEMBL838141 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TSHRTDP1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710260-B2 | Process for preparing substituted aromatic carboxylic acids | PERKINELMER HEALTH SCIENCES, INC. (US) | 2014-04-29 | — | — | US | disclosed |
| US-8426102-B2 | Lithographic printing plate precursor and plate making method | FUJIFILM CORPORATION (JP) | 2013-04-23 | — | — | US | disclosed |
| US-8309294-B2 | — | — | 2012-11-13 | — | — | US | disclosed |
| US-8211678-B2 | Ethanol preparation method | HONDA MOTOR CO., LTD. (JP) | 2012-07-03 | — | — | US | disclosed |
| US-8167144-B2 | Water separation membrane | HONDA MOTOR CO., LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| US-8088548-B2 | Bottom antireflective coating compositions | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20100228048-A1 | PROCESS FOR PREPARING SUBSTITUTED AROMATIC CARBOXYLIC ACIDS | PERKINELMER HEALTH SCIENCES, INC. (US) | 2010-09-09 | — | — | US | disclosed |
| US-20100006496-A1 | WATER SEPARATION MEMBRANE | HONDA MOTOR CO., LTD. (JP) | 2010-01-14 | — | — | US | disclosed |
| US-20100009422-A1 | ETHANOL PREPARATION METHOD | HONDA MOTOR CO., LTD. (JP) | 2010-01-14 | — | — | US | disclosed |
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | MERCK PATENT GMBH (DE) | 2009-04-23 | — | — | US | disclosed |
| US-20080318155-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD | FUJIFILM CORPORATION (JP) | 2008-12-25 | — | — | US | disclosed |
| US-7416593-B2 | 2-[5-Amino-3-methyl-1-phenylpyrazol-4-yl-]-azobenzothiazole derivatives; ink jet printing for paper substrates; brilliant yellow shade; colorfastness, photostability, ozone resistance | CLARIANT FINANCE (BVI) LIMITED (VG) | 2008-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | SDC2, S100A9, MYH9 | ALDH1A1 3154/4885HSD17B10 4444/4885TSHR 4603/4885 |
| US-20100228048-A1 | PROCESS FOR PREPARING SUBSTITUTED AROMATIC CARBOXYLIC ACIDS | PAH, HAO2, DDC | ALDH1A1 107/4885HSD17B10 423/4885TSHR 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.