Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29159126 | 1.00 | ALDH1A1 (0.39) | ALDH1A1EPHX2SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL12610926 | 1.00 | ALDH1A1 (0.39) | ALDH1A1EPHX2SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL12024467 | 1.00 | ALDH1A1 (0.39) | ALDH1A1EPHX2SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL6389608 | 1.00 | ALDH1A1 (0.39) | ALDH1A1EPHX2SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL1527311 | 1.00 | ALDH1A1 (0.39) | ALDH1A1EPHX2SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL14367329 | 1.00 | ALDH1A1 (0.39) | ALDH1A1EPHX2SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL18543456 | 1.00 | ALDH1A1 (0.39) | ALDH1A1EPHX2SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL1933742 | 1.00 | ALDH1A1 (0.39) | ALDH1A1EPHX2SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL542034 | 1.00 | ALDH1A1 (0.39) | ALDH1A1EPHX2SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL838671 | 1.00 | ALDH1A1 (0.39) | ALDH1A1EPHX2SIGMAR1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12104106-B2 | Compositions of chiral molecules and perovskite nanocrystals and methods of making the same | ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) | 2024-10-01 | — | — | US | claimed |
| US-20220326082-A1 | CHIRAL HETEROSTRUCTURES | Alliance for Energy Innovation, LLC | 2022-10-13 | — | — | US | claimed |
| US-7388098-B2 | Dynamic resolution of isomers and resolved isomers | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-06-17 | — | — | US | claimed |
| US-7109377-B2 | Synthesis of combinatorial libraries of compounds reminiscent of natural products | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2006-09-19 | — | — | US | claimed |
| US-20030082830-A1 | Synthesis of combinatorial libraries of compounds reminiscent of natural products | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-05-01 | — | — | US | claimed |
| US-20020111512-A1 | Dynamic resolution of isomers and resolved isomers | BRISTOL-MYERS SQUIBB COMPANY | 2002-08-15 | — | — | US | claimed |
| WO-2000006525-A9 | SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS | HARVARD COLLEGE (US) | 2000-04-20 | — | — | WO | claimed |
| WO-2000006525-A2 | SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2000-02-10 | — | — | WO | claimed |
| US-5440062-A | One-(substituted)amino-7-(substituted)imino-1,3,5-cycloheptatriene-metal complexes as catalysts | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1995-08-08 | — | — | US | claimed |
| WO-1989010916-A1 | ENANTIOSELECTIVE ADDITION OF HYDROCARBONS TO ALPHA,BETA-UNSATURATED CARBONYL COMPOUNDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1989-11-16 | — | — | WO | claimed |
| EP-4143185-B1 | NEW IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1 AND/OR CLK4 | PERHA PHARMACEUTICALS (FR) | 2025-10-29 | — | — | EP | disclosed |
| US-12398129-B2 | Imidazolone derivatives as inhibitors of protein kinases in particular DYRK1A, CLK1 and/or CLK4 | PERHA PHARMACEUTICALS (FR) | 2025-08-26 | — | — | US | disclosed |
| EP-4568945-A1 | HALOPHTHALIMIDE COMPOUNDS AND METHODS OF USE AGAINST TBI, INFLAMMATORY DISORDER, AUTOIMMUNE DISORDER, NEURODEGENERATIVE DISEASE OR VIRAL INFECTION | The United States of America, as represented by The Secretary, Department of Health and Human Services (US) | 2025-06-18 | — | — | EP | disclosed |
| US-12289941-B2 | Chiral heterostructures | ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) | 2025-04-29 | — | — | US | disclosed |
| US-20240383856-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2024-11-21 | — | — | US | disclosed |
| EP-0699186-A1 | INDOLE DERIVATIVES AS ANTAGONISTS OF EXCITATORY AMINO ACIDS | GLAXO S.p.A. (IT) | 1996-03-06 | — | — | EP | disclosed |
| WO-1995029909-A1 | NOVEL ACYCLIC AND CYCLIC AMIDES AS NEUROTRANSMITTER RELEASE ENHANCERS | PFIZER INC. (US) | 1995-11-09 | — | — | WO | disclosed |
| WO-1994020465-A1 | INDOLE DERIVATIVES AS ANTAGONISTS OF EXCITATORY AMINO ACIDS | GLAXO S.P.A. (IT) | 1994-09-15 | — | — | WO | disclosed |
| US-4855432-A | HYDROGENATION CATALYST IN TRANSFER HYDROGENATION OF PROCHIRAL KETONES | CIBA-GEIGY CORPORATION (US) | 1989-08-08 | — | — | US | disclosed |
| US-4851534-A | ENANTIOSELECTIVE HYDROGENATION CATALYST | CIBA-GEIGY CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383856-A1 | INHIBITORS OF TRANSGLUTAMINASES | TGM2, TGM3, TGM1 | ALDH1A1 1825/4885EPHX2 638/4885SIGMAR1 4880/4885 |
| US-20020111512-A1 | Dynamic resolution of isomers and resolved isomers | DHCR24, LPAR1, SLC7A1 | ALDH1A1 1123/4885EPHX2 104/4885SIGMAR1 291/4885 |
| US-12398129-B2 | Imidazolone derivatives as inhibitors of protein kinases in particular DYRK1A, CLK1 and/or CLK4 | CLK1, CLK2, CLK4 | ALDH1A1 2571/4885EPHX2 4511/4885SIGMAR1 3254/4885 |
| US-20030082830-A1 | Synthesis of combinatorial libraries of compounds reminiscent of natural products | TKFC, NISCH, PTGIS | ALDH1A1 568/4885EPHX2 7/4885SIGMAR1 2762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.