SCHEMBL839208

SCHEMBL839208

COc1ccc(C=CC(=O)OCc2ccccc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.75
AKR1B10 O60218 3/20 0.74
AKR1B1 P15121 3/20 0.74
CA12 O43570 2/20 0.74
CA4 P22748 2/20 0.74
CA6 P23280 2/20 0.74
CA5A P35218 2/20 0.74
CA7 P43166 2/20 0.74
CA9 Q16790 2/20 0.74
CA14 Q9ULX7 2/20 0.74
CA5B Q9Y2D0 2/20 0.74
MAPT P10636 2/20 0.68
MAOB P27338 2/20 0.64
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
GSK3B P49841 2/20 0.63
BACE1 P56817 1/20 0.63
TTR P02766 1/20 0.63
TDP1 Q9NUW8 1/20 0.59
BCHE P06276 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17603656 1.00 LMNA (0.75) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL16689983 0.94 LMNA (0.75) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL16689985 0.94 LMNA (0.75) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL20357985 0.90 MAPT (0.78) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL20357986 0.90 MAPT (0.78) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL13552179 0.89 LMNA (0.93) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL28388377 0.88 LMNA (0.79) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL2239306 0.87 MAOB (0.63) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL435192 0.87 MAOB (0.63) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL435193 0.87 MAOB (0.63) LMNAAKR1B10AKR1B1CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3838257-B1 COSMETIC CONTAINING A CARBOXYLIC ACID MODIFIED SILICONE DOW TORAY CO LTD (JP) 2026-01-07 EP disclosed
EP-3838249-B1 OIL-IN-WATER EMULSION COSMETIC COMPOSITION CONTAINING A CARBOXYLIC ACID MODIFIED SILICONE DOW TORAY CO LTD (JP) 2026-01-07 EP disclosed
US-12502345-B2 Cosmetic DOW TORAY CO., LTD. (JP) 2025-12-23 US disclosed
US-12453694-B2 Cosmetic composition DOW TORAY CO., LTD. (JP) 2025-10-28 US disclosed
US-12414908-B2 Cosmetic Sano Co., Ltd. (JP) 2025-09-16 US disclosed
WO-2025087220-A1 METHOD FOR PREPARING (2S,3R)-2-SUBSTITUTED AMINO-3-HYDROXY-3-(4-METHOXYPHENYL)PROPIONATE 科辉智药(深圳)新药研究中心有限公司 2025-05-01 WO disclosed
WO-2024225105-A1 COSMETIC, METHOD FOR PRODUCING SAME, AND ULTRAVIOLET SHIELDING AGENT COMPOSITION ジェイオーコスメティックス株式会社 2024-10-31 WO disclosed
US-12023403-B2 Oil-in-water type emulsion cosmetics DOW TORAY CO., LTD. (JP) 2024-07-02 US disclosed
CN-113710226-B Cosmetic material 陶氏东丽株式会社 2024-02-27 CN disclosed
CN-117466780-A Preparation method of (2S, 3R) -2-substituted amino-3-hydroxy-3- (4-methoxyphenyl) propionate 科辉智药(深圳)新药研究中心有限公司 2024-01-30 CN disclosed
EP-1634564-B2 Cosmetic preparation comprising a crosslinked (meth)acrylic acid ester resin powder KAO CORP (JP) 2013-06-26 EP disclosed
CN-103120625-A Water-in-oil type emulsified cosmetic and skin care method KAO CORP 2013-05-29 CN disclosed
US-8142768-B2 Cosmetic preparation KAO CORPORATION (JP) 2012-03-27 US disclosed
CN-1781475-B Cosmetics KAO CORP 2010-05-12 CN disclosed
EP-1634564-B1 Cosmetic preparation comprising a crosslinked (meth)acrylic acid ester resin powder KAO CORP (JP) 2010-01-06 EP disclosed
US-20080095721-A1 Natural sunscreen compositions and processes for producing the same HIMALAYA GLOBAL HOLDINGS LIMITED (AE) 2008-04-24 US disclosed
US-7311896-B2 Natural sunscreen compositions and processes for producing the same MMI CORPORATION (KY) 2007-12-25 US disclosed
CN-1781475-A Cosmetics KAO CORP (JP) 2006-06-07 CN disclosed
EP-1634564-A1 Cosmetic preparation comprising a crosslinked (meth)acrylic acid ester resin powder Kao Corporation (JP) 2006-03-15 EP disclosed
US-20050266057-A1 Cosmetic preparation KAO CORPORATION (JP) 2005-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12023403-B2 Oil-in-water type emulsion cosmetics CUTA, MITF, POLQ LMNA 1146/4885AKR1B10 4783/4885AKR1B1 4758/4885
US-20050266057-A1 Cosmetic preparation CUTA, FANCF, ASH2L LMNA 3352/4885AKR1B10 1992/4885AKR1B1 2036/4885
US-12453694-B2 Cosmetic composition CUTA, SLC30A7, SLC39A7 LMNA 1474/4885AKR1B10 4162/4885AKR1B1 4255/4885
US-12502345-B2 Cosmetic CUTA, LIPA, PLIN5 LMNA 933/4885AKR1B10 3324/4885AKR1B1 3551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.