Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | PPARD | Q03181 | 1/20 | 0.58 |
| ▸ | PPARA | Q07869 | 1/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160654 | 0.88 | ATM (0.61) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL11044914 | 0.87 | CALM1 (0.67) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL16641094 | 0.87 | CYP19A1 (0.77) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL31157848 | 0.87 | CYP19A1 (0.77) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL7186374 | 0.86 | ATM (0.59) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL7191665 | 0.85 | ATM (0.58) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL10335393 | 0.85 | CYP19A1 (0.81) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL10343404 | 0.83 | ATM (0.70) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL30869991 | 0.83 | ATM (0.70) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL217601 | 0.83 | CA2 (0.68) | ATMKDM4ECA2POLBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207253-A1 | Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2024-06-27 | — | — | US | claimed |
| WO-2022245951-A1 | INHIBITORS OF CDR1 FOR REVERSAL OF AZOLE DRUG RESISTANCE IN FUNGAL INFECTIONS | UNM RAINFOREST INNOVATIONS (US) | 2022-11-24 | — | — | WO | claimed |
| CN-110563602-A | rosmarinic acid derivatives, and preparation method and application thereof | 南宁多灵生物科技有限公司 | 2019-12-13 | — | — | CN | claimed |
| CN-101821246-B | Tetrazole-substituted arylamide derivatives and uses thereof | HOFFMANN LA ROCHE | 2013-05-01 | — | — | CN | claimed |
| CN-101500994-B | 1,3-disubstituted 4-methyl-1h-pyrrole-2-carboxamides and their use for the manufacture of medicaments | GRUENENTHAL GMBH | 2012-12-12 | — | — | CN | claimed |
| CN-101821246-A | Tetrazole-substituted arylamide derivatives and uses thereof | HOFFMANN LA ROCHE | 2010-09-01 | — | — | CN | claimed |
| EP-1626043-B1 | Heterocyclic thioesters | MGI GP INC (US) | 2007-12-12 | — | — | EP | claimed |
| EP-1626043-A1 | Heterocyclic thioesters | MGI GP, Inc. (US) | 2006-02-15 | — | — | EP | claimed |
| US-20050059693-A1 | Heterocyclic thioester and ketone hair growth compositions and uses | GPI NIL HOLDINGS, INC. | 2005-03-17 | — | — | US | claimed |
| US-6818643-B1 | 3,9-DIAZABICYCLO(3.3.1)NONAN-2-ONE DERIVATIVES; PEPTIDYL-PROLYL ISOMERASE (PPIASE OR ROTAMASE) INHIBITORS; NEUROPROTECTIVE AGENTS | BRISTOL-MYERS SQUIBB COMPANY | 2004-11-16 | — | — | US | claimed |
| US-5976894-A | FOR SCREENING BIOASSAYS TO DISCOVER BIOLOGICALLY ACTIVE MEMBERS | PHARMACOPEIA, INC. (US) | 1999-11-02 | — | — | US | claimed |
| EP-0700383-B1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX INC (US) | 1998-09-23 | — | — | EP | claimed |
| WO-1998034113-A1 | COMBINATORIAL LIBRARIES OF BICYCLIC GUANIDINE DERIVATIVES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| US-5786448-A | FOR SCREENING, SYNTHESIZING PEPTIDE DERIVATIVES | TREGA BIOSCIENCES, INC. (US) | 1998-07-28 | — | — | US | claimed |
| US-5763458-A | NERVOUS SYSTEM DISORDERS, ANXIETY, ANTIDEPRESSANTS AND COGNITION ACTIVATORS | SYNTEX (U.S.A.) INC. (US) | 1998-06-09 | — | — | US | claimed |
| WO-1998019693-A1 | COMBINATORIAL LIBRARIES OF CYCLIC UREA AND CYCLIC THIOUREA DERIVATIVES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-05-14 | — | — | WO | claimed |
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | claimed |
| WO-1994027965-A1 | NOVEL 1-PHENYLALKANONE 5-HT4 RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1994-12-08 | — | — | WO | claimed |
| EP-0131509-A2 | Photographic element containing a polymeric mordant comprising quaternized vinylimidazole and acrylonitrile recurring units | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-01-16 | — | — | EP | claimed |
| US-4450224-A | CATIONIC IMIDAZOLE-CONTAINING VINYL POLYMERS FOR SILVER HALIDE COLOR FILMS | EASTMAN KODAK COMPANY (US) | 1984-05-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059693-A1 | Heterocyclic thioester and ketone hair growth compositions and uses | ACOT7, HSD17B7, ZDHHC7 | ATM 4562/4885KDM4E 485/4885CA2 2928/4885 |
| US-20240207253-A1 | Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections | ABCC1, ABCC2, ERG28 | ATM 3188/4885KDM4E 3201/4885CA2 1606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.