Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | PPARD | Q03181 | 1/20 | 0.62 |
| ▸ | PPARA | Q07869 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.52 |
| ▸ | LDHA | P00338 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2125045 | 0.86 | CALM1 (0.61) | CA2ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL11030247 | 0.86 | CALM1 (0.53) | CA2ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL7791117 | 0.85 | SMN1; SMN2 (0.50) | CA2ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL839475 | 0.83 | ATM (0.66) | CA2ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL28220576 | 0.83 | CRHBP (0.50) | CA2ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL1486318 | 0.82 | CA2 (0.68) | CA2ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL9461156 | 0.82 | ALDH1A1 (0.58) | CA2ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL7791111 | 0.82 | ALDH1A1 (0.52) | CA2ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL7791820 | 0.82 | MEN1 (0.51) | CA2ALDH1A1PPARAKDM4ECYP1A2 | |
| SCHEMBL7400462 | 0.82 | CA2 (0.47) | CA2ALDH1A1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207253-A1 | Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2024-06-27 | — | — | US | claimed |
| WO-2024052356-A1 | INHIBITORS OF THE CERAMIDE METABOLIC PATHWAY FOR OVERCOMING IMMUNOTHERAPY RESISTANCE IN CANCER | Institut National de la Santé et de la Recherche Médicale (FR) | 2024-03-14 | — | — | WO | claimed |
| WO-2022245951-A1 | INHIBITORS OF CDR1 FOR REVERSAL OF AZOLE DRUG RESISTANCE IN FUNGAL INFECTIONS | UNM RAINFOREST INNOVATIONS (US) | 2022-11-24 | — | — | WO | claimed |
| CN-113768936-A | Application of evodiamine derivative in preparation of medicine for treating superficial fungal infection | 南华大学 | 2021-12-10 | — | — | CN | claimed |
| CN-113683615-A | Evodiamine derivative and preparation and application thereof | 南华大学 | 2021-11-23 | — | — | CN | claimed |
| CN-106674085-B | Synthesis method of N-1, 3-difluoro isopropyl-4-aminopiperidine compound | 苏州汉德创宏生化科技有限公司 | 2020-06-23 | — | — | CN | claimed |
| CN-110105245-A | A kind of preparation method of Vernakalant intermediate 3,4- Dimethoxyphenethyl 2,2,2- tribromo-acetyl imines | 北京哈三联科技有限责任公司 | 2019-08-09 | — | — | CN | claimed |
| CN-108822127-A | 4- hydroxyl imido grpup thieno [2,3-b] thiapyran -2- Carbox amide and application thereof | 沈阳药科大学 | 2018-11-16 | — | — | CN | claimed |
| EP-3050871-B1 | NOVEL BIS-AMIDE DERIVATIVE AND USE THEREOF | UNIV INDUSTRY COOPERATION GROUP KYUNG HEE UNIV (KR) | 2018-11-07 | — | — | EP | claimed |
| CN-108586484-A | Thieno thiapyran Carbox amide and its application | 沈阳药科大学 | 2018-09-28 | — | — | CN | claimed |
| EP-0011483-A1 | Azocine compounds suitable as analgesics, and process for their production | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1980-05-28 | — | — | EP | claimed |
| EP-0008045-A1 | (1,2)-Annellated 7-phenyl-1,4-benzodiazepine derivatives and salts thereof, processes for their preparation and medicaments containing them | Kali-Chemie Pharma GmbH (DE) | 1980-02-20 | — | — | EP | claimed |
| EP-0002792-A1 | 3-Aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them | SANDOZ AG (CH) | 1979-07-11 | — | — | EP | claimed |
| US-4029650-A | VASODILATORS | DELALANDE S. A. (FR) | 1977-06-14 | — | — | US | claimed |
| US-4024156-A | Thiophene ethanolamines | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-05-17 | — | — | US | claimed |
| US-4001421-A | THIAZOLE CARDIOVASCULAR AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-01-04 | — | — | US | claimed |
| US-3982010-A | Thiazole cardiovascular agents | SYNTEX (U.S.A.) INC. (US) | 1976-09-21 | — | — | US | claimed |
| US-3954774-A | HYPOTENSIVE AGENTS | MARION LABORATORIES, INC. (US) | 1976-05-04 | — | — | US | claimed |
| US-3953596-A | 8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals | ICI UNITED STATES INC. (US) | 1976-04-27 | — | — | US | claimed |
| US-3936454-A | ANTIANGINAL, BRONCHODILATOR | WARNER-LAMBERT COMPANY (US) | 1976-02-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240207253-A1 | Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections | ABCC1, ABCC2, ERG28 | CA2 1606/4885ALDH1A1 3934/4885PPARG 4078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.