Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.47 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8481530 | 0.99 | TPSAB1 (0.55) | TPSAB1ALDH1A1HDAC6HDAC2HDAC8 | |
| SCHEMBL8395856 | 0.87 | HDAC2 (0.51) | TPSAB1ALDH1A1HDAC6HDAC2HDAC8 | |
| SCHEMBL8581493 | 0.86 | NPC1 (0.56) | TPSAB1RAB9APOLB | |
| SCHEMBL8392174 | 0.80 | TPSAB1 (0.53) | TPSAB1TPSD1TPSG1 | |
| SCHEMBL8583853 | 0.78 | HIF1A (0.57) | POLB | |
| SCHEMBL8395271 | 0.77 | ALDH1A1 (0.58) | TPSAB1ALDH1A1LMNARAB9APOLB | |
| SCHEMBL8394020 | 0.76 | HDAC3 (0.53) | TPSAB1ALDH1A1HDAC6HDAC2HDAC8 | |
| SCHEMBL3808704 | 0.76 | HPGD (0.64) | ALDH1A1HDAC6HDAC2HDAC8HPGD | |
| Hydrochloric Acid SCHEMBL8397093 | 0.75 | HDAC3 (0.52) | TPSAB1ALDH1A1HDAC6HDAC2HDAC8 | |
| SCHEMBL8518311 | 0.75 | SIGMAR1 (0.54) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690851-B1 | GUANIDINE DERIVATIVES USEFUL IN THERAPY | ASTRA AB (SE) | 1999-05-19 | — | — | EP | claimed |