Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399032 | 0.97 | THRA (0.45) | THRATHRBPPARDCYP3A4CYP1A2 | |
| SCHEMBL8396234 | 0.94 | PPARD (0.39) | THRATHRBPPARDCYP3A4BCHE | |
| SCHEMBL8398724 | 0.91 | NISCH (0.38) | THRBCYP3A4LMNASNCA | |
| SCHEMBL8400210 | 0.88 | THRA (0.41) | THRATHRBPPARDCYP3A4CYP1A2 | |
| SCHEMBL8395408 | 0.86 | CYP3A4 (0.43) | CYP3A4LMNA | |
| SCHEMBL8397742 | 0.85 | THRA (0.46) | THRATHRBPPARDPTGER1PTGER4 | |
| SCHEMBL8399060 | 0.85 | TP53 (0.45) | THRBLTB4RLTB4R2LMNA | |
| SCHEMBL8399129 | 0.85 | LMNA (0.41) | THRBCYP3A4LTB4RLTB4R2LMNA | |
| SCHEMBL8519936 | 0.83 | NISCH (0.36) | CYP3A4CYP1A2CYP2C19PPARALMNA | |
| SCHEMBL8395164 | 0.83 | CYP3A4 (0.41) | CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |