Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397947 | 0.81 | PDE4A (0.31) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL8396268 | 0.81 | AKR1B1 (0.41) | AKR1B1ALDH1A1MAPT | |
| SCHEMBL8395826 | 0.81 | AKR1B1 (0.41) | AKR1B1 | |
| SCHEMBL8395524 | 0.80 | AKR1B1 (0.43) | AKR1B1KDM4EALDH1A1MAPT | |
| SCHEMBL8399262 | 0.79 | AKR1B1 (0.40) | AKR1B1KDM4EALDH1A1MAPT | |
| SCHEMBL8396103 | 0.78 | AKR1B1 (0.41) | AKR1B1KDM4EALDH1A1MAPT | |
| SCHEMBL8399286 | 0.77 | AKR1B1 (0.39) | AKR1B1KDM4EALDH1A1MAPT | |
| SCHEMBL8395489 | 0.77 | AKR1B1 (0.39) | AKR1B1KDM4EALDH1A1MAPT | |
| SCHEMBL8395800 | 0.77 | AKR1B1 (0.41) | AKR1B1 | |
| SCHEMBL8399103 | 0.76 | L3MBTL1 (0.43) | AKR1B1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |