Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403511 | 0.82 | L3MBTL1 (0.58) | ALDH1A1L3MBTL1LMNAHIF1AMEN1 | |
| SCHEMBL8399433 | 0.81 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1GAAAPLNRNPC1 | |
| SCHEMBL8401523 | 0.76 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1GAAKDM4EAPLNR | |
| SCHEMBL8399558 | 0.76 | ALDH1A1 (0.39) | ALDH1A1GAAKDM4EAPLNRLMNA | |
| SCHEMBL8399521 | 0.74 | ALDH1A1 (0.42) | ALDH1A1GAAAPLNRNPC1RAB9A | |
| SCHEMBL8402601 | 0.72 | ALDH1A1 (0.40) | ALDH1A1GAAKDM4EAPLNRNPC1 | |
| SCHEMBL8403524 | 0.72 | APLNR (0.45) | ALDH1A1GAAAPLNRLMNA | |
| SCHEMBL8399519 | 0.68 | USP2 (0.37) | ALDH1A1L3MBTL1GAAKDM4EAPLNR | |
| SCHEMBL1253501 | 0.67 | ALDH1A1 (0.50) | ALDH1A1GAANPC1RAB9ALMNA | |
| SCHEMBL27754527 | 0.67 | CA1 (0.44) | ALDH1A1L3MBTL1GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885997-A | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-03-23 | — | — | US | disclosed |