Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | APLNR | P35414 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399558 | 0.92 | ALDH1A1 (0.39) | ALDH1A1GAAAPLNRBCAT2PKM | |
| SCHEMBL8402601 | 0.90 | ALDH1A1 (0.40) | ALDH1A1GAAAPLNRSMN1; SMN2NPC1 | |
| SCHEMBL8403524 | 0.90 | APLNR (0.45) | ALDH1A1GAAAPLNRLMNAMAPT | |
| SCHEMBL8399521 | 0.89 | ALDH1A1 (0.42) | ALDH1A1GAAAPLNRBCAT2PKM | |
| SCHEMBL8399519 | 0.87 | USP2 (0.37) | ALDH1A1GAAAPLNRL3MBTL1SMN1; SMN2 | |
| SCHEMBL8401523 | 0.86 | ALDH1A1 (0.40) | ALDH1A1GAAAPLNRL3MBTL1SMN1; SMN2 | |
| SCHEMBL8399369 | 0.81 | ALDH1A1 (0.38) | ALDH1A1GAAAPLNRL3MBTL1LMNA | |
| SCHEMBL8399362 | 0.80 | ALDH1A1 (0.47) | ALDH1A1GAAL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL8403511 | 0.79 | L3MBTL1 (0.58) | ALDH1A1L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL1253501 | 0.68 | ALDH1A1 (0.50) | ALDH1A1GAASMN1; SMN2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885997-A | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-03-23 | — | — | US | disclosed |