Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | APLNR | P35414 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399433 | 0.87 | ALDH1A1 (0.41) | LMNAAPLNRALDH1A1MEN1KMT2A | |
| SCHEMBL8399558 | 0.80 | ALDH1A1 (0.39) | USP2LMNAAPLNRALDH1A1MEN1 | |
| SCHEMBL8403524 | 0.78 | APLNR (0.45) | LMNAAPLNRALDH1A1MAPTGAA | |
| SCHEMBL8402601 | 0.78 | ALDH1A1 (0.40) | APLNRALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL8399521 | 0.77 | ALDH1A1 (0.42) | LMNAAPLNRALDH1A1MEN1KMT2A | |
| SCHEMBL8399362 | 0.76 | ALDH1A1 (0.47) | LMNARECQLALDH1A1MEN1KMT2A | |
| SCHEMBL8401523 | 0.74 | ALDH1A1 (0.40) | APLNRALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8399369 | 0.68 | ALDH1A1 (0.38) | HPGDLMNAAPLNRALDH1A1MEN1 | |
| SCHEMBL8403511 | 0.67 | L3MBTL1 (0.58) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5935702 | 0.65 | KMT2A (0.49) | HPGDTSHRLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885997-A | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-03-23 | — | — | US | disclosed |