SCHEMBL8400350

SCHEMBL8400350

c1ccc(-c2cc(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 6/20 0.53
▸ L3MBTL1 Q9Y468 3/20 0.53
▸ ATM Q13315 1/20 0.53
▸ KMT2A Q03164 10/20 0.53
▸ MEN1 O00255 9/20 0.53
▸ HPGD P15428 9/20 0.53
▸ MAPT P10636 9/20 0.53
▸ ALDH1A1 P00352 8/20 0.53
▸ NTSR1 P30989 1/20 0.53
▸ LMNA P02545 2/20 0.46
▸ GLA P06280 1/20 0.46
▸ ADORA2A P29274 2/20 0.46
▸ ADORA1 P30542 2/20 0.46
▸ NPSR1 Q6W5P4 3/20 0.43
▸ RXFP1 Q9HBX9 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43
▸ MAOA P21397 1/20 0.42
▸ MAOB P27338 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ PTK2B Q14289 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31666 1.00 KDM4E (0.53) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL6374508 1.00 KDM4E (0.53) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL9881125 1.00 KDM4E (0.53) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL10051212 0.98 KDM4E (0.52) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL24398496 0.98 KDM4E (0.52) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL24812016 0.98 KDM4E (0.52) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL8400367 0.98 KDM4E (0.52) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL22763464 0.98 KDM4E (0.52) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL18708348 0.98 KDM4E (0.52) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL24810937 0.98 KDM4E (0.52) KDM4EL3MBTL1ATMKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240244971-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2024-07-18 — — US disclosed
US-20240244871-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2024-07-18 — — US disclosed
US-20240244871-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2024-07-18 — — US disclosed
US-20240244971-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2024-07-18 — — US disclosed
US-12035617-B2 Organic electroluminescence device and organometallic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-09 — — US disclosed
US-12035617-B2 Organic electroluminescence device and organometallic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-09 — — US disclosed
US-20240074311-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-02-29 — — US disclosed
US-20230301175-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-09-21 — — US disclosed
US-20230276698-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-31 — — US disclosed
US-20230276698-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-31 — — US disclosed
US-20070135652-A1 METAL-COMPLEX COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2007-06-14 — — US disclosed
US-20070135652-A1 METAL-COMPLEX COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2007-06-14 — — US disclosed
US-20070108891-A1 METAL-COMPLEX COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2007-05-17 — — US disclosed
US-20070108891-A1 METAL-COMPLEX COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2007-05-17 — — US disclosed
US-20070111024-A1 Metal complex compound and organic electroluminescence device containing the same IDEMITSU KOSAN CO., LTD. (JP) 2007-05-17 — — US disclosed
US-20070111024-A1 Metal complex compound and organic electroluminescence device containing the same IDEMITSU KOSAN CO., LTD. (JP) 2007-05-17 — — US disclosed
US-20070069638-A1 Blue organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2007-03-29 — — US disclosed
US-20070069638-A1 Blue organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2007-03-29 — — US disclosed
US-20070013295-A1 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2007-01-18 — — US disclosed
US-20070013295-A1 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2007-01-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12035617-B2 Organic electroluminescence device and organometallic compound for organic electroluminescence device OR10J3, LEF1, PIEZO1 KDM4E 1161/4885L3MBTL1 616/4885ATM 3134/4885
US-20070135652-A1 METAL-COMPLEX COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE COMPOUND EMC2, EMC1, L1CAM KDM4E 1456/4885L3MBTL1 555/4885ATM 3001/4885
US-20240074311-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE RPS12, TCF12, RRP12 KDM4E 2161/4885L3MBTL1 785/4885ATM 3325/4885
US-20070108891-A1 METAL-COMPLEX COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE COMPOUND EMC2, LAGE3, EPCAM KDM4E 1142/4885L3MBTL1 157/4885ATM 3009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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