Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398839 | 0.71 | PARP1 (0.41) | PARP1PARP2MAPK1MTNR1AMTNR1B | |
| SCHEMBL7398372 | 0.70 | ITGB3 (0.40) | — | |
| SCHEMBL8401258 | 0.70 | PARK7 (0.31) | MAPK1SMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7353946 | 0.67 | NR4A1 (0.51) | MAPK1L3MBTL1 | |
| SCHEMBL7398374 | 0.67 | ITGB3 (0.46) | SMN1; SMN2HDAC6 | |
| SCHEMBL7356370 | 0.66 | RAB9A (0.49) | NPC1RAB9AGAAMAPK1SMN1; SMN2 | |
| SCHEMBL8401201 | 0.63 | NPC1 (0.37) | TMEM97SIGMAR1NPC1RAB9AL3MBTL1 | |
| SCHEMBL8402406 | 0.60 | ALDH1A1 (0.59) | MAPK1L3MBTL1 | |
| SCHEMBL13041634 | 0.57 | PARP1 (0.43) | PARP1PARP2RAB9AGAAL3MBTL1 | |
| SCHEMBL3846207 | 0.55 | ALDH1A1 (0.70) | NPC1RAB9AMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |