Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.35 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896502 | 0.81 | MIF (0.48) | NPC1RAB9AL3MBTL1KMT2AMAPT | |
| SCHEMBL7353946 | 0.68 | NR4A1 (0.51) | L3MBTL1KMT2AMAPTMEN1LMNA | |
| SCHEMBL7356370 | 0.67 | RAB9A (0.49) | NPC1RAB9AL3MBTL1KMT2AMAPT | |
| SCHEMBL7398115 | 0.66 | ITGB3 (0.56) | NPC1RAB9A | |
| SCHEMBL8401257 | 0.63 | PARP1 (0.35) | NPC1RAB9AL3MBTL1CHRNB2CHRNA4 | |
| SCHEMBL7591583 | 0.63 | CHRNB2 (0.45) | NPC1RAB9AL3MBTL1CHRNB2CHRNA7 | |
| SCHEMBL8402406 | 0.61 | ALDH1A1 (0.59) | L3MBTL1KMT2ACYP3A4LMNASLC6A2 | |
| SCHEMBL27616400 | 0.59 | NPC1 (0.84) | NPC1RAB9AL3MBTL1NOTUMKMT2A | |
| SCHEMBL16553615 | 0.58 | NPC1 (0.46) | NPC1RAB9AL3MBTL1NOTUMKMT2A | |
| SCHEMBL3431999 | 0.58 | PREP (0.46) | NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |