Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401557 | 0.85 | ALOX5 (0.51) | ALOX5MAPTKDM4ETP53CYP3A4 | |
| SCHEMBL7796420 | 0.79 | TPMT (0.39) | ALDH1A1HSD17B10RARGRXRAPPARG | |
| SCHEMBL7795934 | 0.77 | THRB (0.39) | ALDH1A1GAAHSD17B10RXRAPPARG | |
| SCHEMBL6565884 | 0.75 | MAPT (0.35) | MAPTCYP3A4CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL7794852 | 0.75 | THRA (0.40) | RXRAKMT2APOLB | |
| SCHEMBL6565863 | 0.74 | TNKS2 (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7944996 | 0.73 | CYP3A4 (0.39) | LMNAMAPK1CYP3A4MEN1KMT2A | |
| SCHEMBL12799798 | 0.71 | ALOX5 (0.49) | ALOX5TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL15180049 | 0.71 | CA1 (0.50) | ALDH1A1GAA | |
| SCHEMBL7942500 | 0.70 | KMT2A (0.37) | ALOX5MAPTALDH1A1GAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |