Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | ATP4A | P20648 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406507 | 0.88 | MMP2 (0.34) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL8698688 | 0.87 | MMP2 (0.34) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL7658367 | 0.85 | MMP2 (0.35) | MMP2MMP9MMP8MMP13MEN1 | |
| SCHEMBL8404112 | 0.83 | MMP2 (0.34) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL8401940 | 0.79 | ACHE (0.31) | FPR2MEN1SLC22A1ABCB11LMNA | |
| SCHEMBL7670523 | 0.79 | MMP2 (0.36) | MMP2MMP9MMP8MMP13LMNA | |
| SCHEMBL8066300 | 0.78 | MMP2 (0.35) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL7667177 | 0.78 | MMP2 (0.35) | MMP2MMP9MMP8MMP13FPR2 | |
| SCHEMBL7662040 | 0.77 | FPR2 (0.37) | MMP2MMP9MMP8MMP13FPR2 | |
| SCHEMBL8401715 | 0.77 | FAAH (0.38) | MEN1CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935981-A | INSECTICIDAL/MITICIDAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5849768-A | α-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-15 | — | — | US | disclosed |