Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 9/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8519840 | 0.75 | MAPT (0.40) | L3MBTL1 | |
| SCHEMBL8518520 | 0.71 | MAPT (0.39) | — | |
| SCHEMBL8398754 | 0.63 | S1PR1 (0.32) | — | |
| SCHEMBL8401237 | 0.62 | CACNA1G (0.35) | — | |
| SCHEMBL7395503 | 0.62 | ALDH1A1 (0.37) | — | |
| SCHEMBL8518894 | 0.60 | BRD4 (0.31) | — | |
| SCHEMBL8402387 | 0.59 | MAPT (0.37) | L3MBTL1 | |
| SCHEMBL20335636 | 0.57 | TRPA1 (0.41) | — | |
| SCHEMBL8523438 | 0.57 | PTGDR2 (0.36) | — | |
| SCHEMBL8475813 | 0.56 | MEN1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |