SCHEMBL8402945

SCHEMBL8402945

Cc1ccc(Oc2cccc(C)c2Oc2ccc(C)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.49
SLC6A4 P31645 3/20 0.46
HTR2A P28223 2/20 0.46
L3MBTL1 Q9Y468 3/20 0.44
ALDH1A1 P00352 4/20 0.42
HTT P42858 3/20 0.42
TEAD4 Q15561 1/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
DHFR P00374 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
CYP2C19 P33261 1/20 0.39
DRD2 P14416 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1345933 0.86 LTA4H (0.44) LMNASLC6A4L3MBTL1ALDH1A1HTT
SCHEMBL11585245 0.82 DHFR (0.57) LMNASLC6A4HTR2AL3MBTL1ALDH1A1
SCHEMBL172615 0.81 HTR2A (0.55) LMNASLC6A4HTR2AL3MBTL1ALDH1A1
SCHEMBL28604976 0.79 HTR2A (0.53) LMNASLC6A4HTR2AL3MBTL1ALDH1A1
SCHEMBL8626752 0.79 LPAR1 (0.58) ALDH1A1HTTPOLBHPGDGAA
SCHEMBL9411536 0.78 ALDH1A1 (0.50) LMNASLC6A4L3MBTL1ALDH1A1HTT
SCHEMBL10981342 0.78 ALDH1A1 (0.48) LMNASLC6A4HTR2AL3MBTL1ALDH1A1
SCHEMBL2608310 0.78 HTT (0.65) LMNASLC6A4HTR2AL3MBTL1ALDH1A1
SCHEMBL24043208 0.75 SLC6A4 (0.49) LMNASLC6A4HTR2AL3MBTL1ALDH1A1
SCHEMBL3874015 0.75 TEAD4 (0.59) LMNASLC6A4HTR2AALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0616897-B1 Process for preparing a heat-sensitive recording material. NICCA CHEMICAL CO (JP) 1999-06-16 EP disclosed
EP-0618082-B1 A heat-sensitive recording material NICCA CHEMICAL CO (JP) 1998-01-21 EP disclosed
US-5378674-A Heat-sensitive recording material NICCA CHEMICAL CO., LTD. (JP) 1995-01-03 US disclosed
EP-0618082-A1 A heat-sensitive recording material NICCA CHEMICAL CO., Ltd. (JP) 1994-10-05 EP disclosed
EP-0616897-A2 A heat-sensitive recording material NICCA CHEMICAL CO., LTD. (JP) 1994-09-28 EP disclosed
US-5348930-A Leuco dye, developer, sensitizer NICCA CHEMICAL CO., LTD. (JP) 1994-09-20 US disclosed