Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.43 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.43 |
| ▸ | CAPNS1 | P04632 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404245 | 0.90 | CAPN1 (0.42) | CAPN1LARS1CAPNS1CYP3A4CYP1A2 | |
| SCHEMBL8403868 | 0.86 | MMP13 (0.45) | HPGDALDH1A1 | |
| SCHEMBL8810086 | 0.86 | CA2 (0.47) | CAPN1CAPNS1TSHRKDM4EMEN1 | |
| SCHEMBL8404227 | 0.86 | CAPN1 (0.54) | CAPN1LARS1CAPNS1MEN1KMT2A | |
| SCHEMBL8404230 | 0.86 | CAPN1 (0.54) | CAPN1LARS1CAPNS1MEN1KMT2A | |
| SCHEMBL8406510 | 0.85 | MMP2 (0.38) | CAPN1CAPNS1MEN1KMT2ALMNA | |
| SCHEMBL8407938 | 0.85 | LARS1 (0.45) | CAPN1LARS1CAPNS1CYP3A4CYP1A2 | |
| SCHEMBL8808273 | 0.82 | SLC1A3 (0.39) | CAPN1CAPNS1MAPTHTR7SLC1A3 | |
| SCHEMBL8406506 | 0.82 | CA1 (0.39) | CAPN1LARS1MAPTMEN1KMT2A | |
| SCHEMBL8811338 | 0.82 | CA1 (0.39) | CAPN1LARS1CAPNS1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |