Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 12/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 3/20 | 0.45 |
| ▸ | MMP1 | P03956 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003864 | 0.82 | MMP2 (0.54) | BMP1MMP1MMP8MMP13 | |
| SCHEMBL8404841 | 0.81 | BMP1 (0.43) | BMP1MEP1BMMP3MMP1MMP8 | |
| SCHEMBL8404013 | 0.79 | ALDH1A1 (0.51) | BMP1MEP1BMMP3MMP1MMP8 | |
| SCHEMBL27504623 | 0.77 | BMP1 (0.44) | BMP1MMP1MMP8ALDH1A1LMNA | |
| SCHEMBL8016814 | 0.72 | MMP2 (0.57) | BMP1MMP3MMP1MMP8MMP13 | |
| SCHEMBL8400807 | 0.72 | ALDH1A1 (0.53) | BMP1MEP1BALDH1A1 | |
| SCHEMBL8554136 | 0.70 | SMN1; SMN2 (0.45) | BMP1MEP1BMMP3MMP1MMP8 | |
| SCHEMBL8403388 | 0.70 | TSHR (0.55) | BMP1MMP1MMP8ALDH1A1LMNA | |
| SCHEMBL8400820 | 0.70 | ALDH1A1 (0.49) | BMP1MMP1MMP8ALDH1A1LMNA | |
| SCHEMBL8405651 | 0.70 | ALDH1A1 (0.49) | BMP1MMP3MMP1MMP8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922030-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998007697-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-02-26 | — | — | WO | disclosed |