SCHEMBL8409019

SCHEMBL8409019

OCCCc1ccccc1OCCCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 1/20 0.54
PTGER4 P35408 1/20 0.54
PTGER3 P43115 1/20 0.54
PTGER2 P43116 1/20 0.54
HTR1A P08908 1/20 0.53
DRD2 P14416 1/20 0.53
LTA4H P09960 1/20 0.53
EPHX2 P34913 1/20 0.53
HRH1 P35367 2/20 0.50
KCNH2 Q12809 1/20 0.49
TP53 P04637 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
TSHR P16473 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
HPGD P15428 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
DHFR P00374 1/20 0.48
LMNA P02545 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24041887 0.92 HTR1A (0.54) PTGER1PTGER4PTGER3PTGER2HTR1A
SCHEMBL5256025 0.88 HTR1A (0.64) HTR1ADRD2KCNH2
SCHEMBL3159332 0.85 HTR1A (0.69) PTGER1PTGER4PTGER3PTGER2HTR1A
SCHEMBL31561714 0.85 HTR1A (0.69) PTGER1PTGER4PTGER3PTGER2HTR1A
SCHEMBL5249495 0.83 HRH1 (0.66) HTR1ADRD2HRH1TP53CYP1A2
SCHEMBL5660184 0.83 HTR1A (0.56) PTGER1PTGER4PTGER3PTGER2HTR1A
SCHEMBL9077676 0.82 MTNR1B (0.47)
SCHEMBL7218033 0.81 LTB4R (0.48) HRH1CYP1A2CYP2C9L3MBTL1HPGD
SCHEMBL10650358 0.81 HTR1A (0.50) PTGER1PTGER4PTGER3PTGER2HTR1A
SCHEMBL10683333 0.80 HTR1A (0.67) PTGER1PTGER4PTGER3PTGER2HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5861437-A CATIONIC POLYPHENYLENE ETHERS FOR ADSORBING BILE ACIDS AND FOR CHOLESTEROL REDUCTION KISSEI PHARMACEUTICAL COMPANY, LTD. (JP) 1999-01-19 US disclosed
EP-0821022-A1 POLYPHENYLENE ETHER RESIN KISSEI PHARMACEUTICAL CO., LTD. (JP) 1998-01-28 EP disclosed