Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4936612 | 0.81 | MEN1 (0.44) | LMNAMCOLN3ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL8412736 | 0.79 | CTSB (0.42) | NPSR1SMN1; SMN2HSD11B1L3MBTL1 | |
| SCHEMBL9305833 | 0.79 | ALDH1A1 (0.38) | ALDH1A1MEN1ESR1KMT2AESR2 | |
| SCHEMBL10891319 | 0.75 | KEAP1 (0.40) | LMNAMCOLN3ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL11711549 | 0.74 | MEN1 (0.45) | LMNAALDH1A1SMN1; SMN2MEN1ESR1 | |
| SCHEMBL14778954 | 0.73 | MEN1 (0.44) | LMNAMCOLN3ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL8412958 | 0.73 | ACHE (0.35) | LMNAMCOLN3ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL8409585 | 0.71 | SMN1; SMN2 (0.35) | LMNAMCOLN3ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL28138262 | 0.71 | CA1 (0.41) | LMNAMCOLN3ALDH1A1NPSR1KEAP1 | |
| SCHEMBL29415231 | 0.71 | ALDH1A1 (0.40) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708087-B1 | Method for making a substituted benzene compound | ROHM & HAAS (US) | 1999-07-28 | — | — | EP | disclosed |
| US-5670691-A | REACTION OF 2-SUBSTITUTED BENZENESULFONATE WITH LITHIUM COMPOUND THEN REACTION WITH ELECTROPHILE TO FORM 2,6-DISUBSTITUTED BENZENESULFONATE | ROHM AND HAAS COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
| EP-0708087-A1 | Method for making a substituted benzene compound | ROHM AND HAAS COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |