Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8412958 | 0.79 | ACHE (0.35) | SMN1; SMN2HTTMEN1LMNAPOLB | |
| SCHEMBL8412736 | 0.76 | CTSB (0.42) | SMN1; SMN2HTTNPSR1L3MBTL1GABRA1 | |
| SCHEMBL8409777 | 0.73 | GABRA1 (0.36) | SMN1; SMN2MEN1KMT2ANR3C1PGR | |
| SCHEMBL8409661 | 0.71 | LMNA (0.38) | SMN1; SMN2MEN1LMNAPOLBKMT2A | |
| SCHEMBL461617 | 0.71 | CA2 (0.42) | NLRP3GABRA1GABRB2PTGS2 | |
| SCHEMBL5886048 | 0.71 | GABRA1 (0.40) | SMN1; SMN2HTTMEN1POLBKMT2A | |
| SCHEMBL1607448 | 0.71 | GABRA1 (0.45) | SMN1; SMN2HTTMEN1POLBKMT2A | |
| SCHEMBL8410853 | 0.70 | NR3C1 (0.35) | LMNAKMT2ANR3C1PGRNR3C2 | |
| SCHEMBL8409580 | 0.68 | LMNA (0.33) | SMN1; SMN2LMNAPOLBNPSR1L3MBTL1 | |
| SCHEMBL27489131 | 0.67 | GABRA1 (0.36) | SMN1; SMN2POLBNR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708087-B1 | Method for making a substituted benzene compound | ROHM & HAAS (US) | 1999-07-28 | — | — | EP | disclosed |
| US-5670691-A | REACTION OF 2-SUBSTITUTED BENZENESULFONATE WITH LITHIUM COMPOUND THEN REACTION WITH ELECTROPHILE TO FORM 2,6-DISUBSTITUTED BENZENESULFONATE | ROHM AND HAAS COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
| EP-0708087-A1 | Method for making a substituted benzene compound | ROHM AND HAAS COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |