Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 12/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 12/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409401 | 0.90 | SLC6A12 (0.42) | SCN1ASCN8AACHEKDM4EOPRM1 | |
| SCHEMBL8409680 | 0.90 | ACHE (0.40) | SCN1ASCN8AACHEKDM4EGAA | |
| SCHEMBL8409257 | 0.88 | SCN1A (0.47) | SCN1ASCN8AKDM4EGAA | |
| SCHEMBL8410128 | 0.86 | GMNN (0.41) | SCN1ASCN8AACHEKDM4EGAA | |
| SCHEMBL8406488 | 0.84 | DRD2 (0.49) | ACHEKDM4EGAAOPRM1SIGMAR1 | |
| SCHEMBL9091787 | 0.82 | CHRM2 (0.42) | SCN1ASCN8AACHEKDM4EGAA | |
| SCHEMBL8406857 | 0.82 | OPRM1 (0.43) | SCN1ASCN8AACHEKDM4EOPRM1 | |
| SCHEMBL8792659 | 0.81 | GMNN (0.38) | SCN1ASCN8AACHEKDM4EGAA | |
| SCHEMBL8406690 | 0.79 | SLC6A2 (0.34) | — | |
| SCHEMBL8406485 | 0.78 | MAPK1 (0.46) | SCN1ASCN8AACHEOPRM1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866589-A | Alkyl substituted piperadinyl and piperazinyl anti-AIDS compounds | PHARMACIA & UPJOHN COMPANY (US) | 1999-02-02 | — | — | US | disclosed |