Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409658 | 0.83 | MAP2K7 (0.34) | ALDH1A1SMN1; SMN2LMNAKMT2AL3MBTL1 | |
| SCHEMBL8412954 | 0.83 | PKM (0.34) | ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8409580 | 0.81 | LMNA (0.33) | ALDH1A1SMN1; SMN2LMNATSHRL3MBTL1 | |
| SCHEMBL8412670 | 0.79 | STK10 (0.36) | SMN1; SMN2KMT2ATSHRMEN1 | |
| SCHEMBL8412812 | 0.77 | ACHE (0.38) | ALDH1A1SMN1; SMN2LMNAKMT2ATSHR | |
| SCHEMBL8732683 | 0.77 | L3MBTL1 (0.31) | SMN1; SMN2LMNAKMT2AL3MBTL1HTT | |
| SCHEMBL8734800 | 0.76 | MAPT (0.30) | LMNAL3MBTL1MAPTTDP1 | |
| SCHEMBL8730138 | 0.75 | ALDH1A1 (0.31) | ALDH1A1TSHRL3MBTL1MAPTTDP1 | |
| SCHEMBL8409656 | 0.75 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2LMNAKMT2AHTT | |
| SCHEMBL8412945 | 0.74 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2LMNAKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708087-B1 | Method for making a substituted benzene compound | ROHM & HAAS (US) | 1999-07-28 | — | — | EP | disclosed |
| US-5670691-A | REACTION OF 2-SUBSTITUTED BENZENESULFONATE WITH LITHIUM COMPOUND THEN REACTION WITH ELECTROPHILE TO FORM 2,6-DISUBSTITUTED BENZENESULFONATE | ROHM AND HAAS COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
| EP-0708087-A1 | Method for making a substituted benzene compound | ROHM AND HAAS COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |